The Gross-to-Net Challenge
Biopharmaceutical finance and market access teams face four critical business challenges: inefficiency and rework, risky manual processes, financial statement errors, and audit and compliance issues. These challenges intensify as teams attempt to accurately accrue the vast number of rebates, discounts, chargebacks, administrative fees, copay programs, and other sales-related adjustments across an increasingly complex commercial landscape.
Common challenges include:
- Inaccuracy of pricing, discount, copay, inventory, and returns data
- Forecasting models lacking a clear, documented, and audit-ready methodology
- Fragile, error-prone spreadsheet models that lack effective version control
- Fragmented data and siloed departments operating from independent GTN spreadsheets
- Difficulty hiring and retaining GTN talent
Proven at Scale
IntegriChain's Gross-to-Net (GTN) solutions leverage ICyte's unified data infrastructure to connect accrual management, forecasting, analytics, and scenario modeling in one secure, auditable platform.
50%
Less effort on end-to-end GTN forecast processes with ICyte
30%
Reduction in audit prep time
550+
Brands powered by ICyte GTN data
Gross-to-Net Accruals
Master Accurate and Automated Gross-to-Net Accrual Management
IntegriChain's GTN Accruals solution automates the entire accrual lifecycle- from data ingestion and cleansing through calculation execution, balance sheet roll-forward, and financial close, eliminating manual processes and delivering the bottoms-up transparency that finance teams and auditors demand. The platform comes pre-configured with accrual methodologies for all standard GTN line items, including prior period true-ups, inventory pipeline adjustments, and a dedicated URA, Best Price, and TRICARE calculator. Seamless integration with revenue management systems and ERP platforms, combined with pre-built operational reports, a full-suite analytics dashboard, and scalability and auditability built in from day one, makes it a comprehensive solution for modern GTN management.
Business Benefits
Quicker Close
Close books in fewer days by eliminating manual data collection and calculation processes.
Easier Audit
Built-in auditability, traceability, and scalability reduces audit prep time by up to 30%.

More Accurate Accruals
Bottoms-up accruals with transparency to details and consistency of models across businesses and brands.
More Secure Environment
Strong access, privacy, and security controls ensure a single version of the truth across all calculations.
Deeper Insights
Advanced analytics and data visualization support brand-level profitability analysis, price/volume analysis, and what-if scenario modeling.
Real-Time Reporting
Advanced analytics and data visualization support brand-level profitability analysis, price/volume analysis, and what-if scenario modeling.
Gross-to-Net Forecasting
Precisely and Confidently Forecast Your Gross-to-Net Accruals and Net Prices
ICyte's industry-leading GTN forecasting capabilities empower finance and market access teams to build and maintain financial models that accurately forecast net revenue by payer and channel, with full visibility into historical inputs, assumptions, and transactions. The platform offers out-of-the-box forecasting methodologies for each GTN line item, a contract and mandated rate repository, and calculators for URA, Best Price, ASP, and TRICARE. Robust what-if scenario modeling captures the net revenue impact of WAC pricing changes, contract term adjustments, legislation, AMP and URA fluctuations, 340B/PHS pricing, and Medicaid program participation, all supported by variance analysis, side-by-side scenario comparison, and pre-configured reports and dashboards.
Business Benefits
Quicker Forecast Cycle
Forecast in fewer days by eliminating manual data collection and calculations.

More Accurate Forecasts
Bottoms-up, transparent forecasts with easy audit trail and access to supporting data and assumptions drive accurate GTN predictions.
Increased Confidence
Make data-driven decisions backed by a comprehensive understanding of net price across all channels and payers.
Enhanced Collaboration
Break down departmental silos with a unified platform where pricing, payer, and co-pay teams contribute inputs and model scenarios together.