Net Revenue Management
Precision Controls. Optimized Performance. Complete Net Revenue Visibility.
Proven at Scale
Our proven solutions are trusted across the industry, supporting hundreds of biopharma organizations managing billions in net sales. The numbers speak for themselves: from Medicaid rebates to distribution contract management, ICyte delivers results at scale.
180+
Managed Services Customers
$230B
Net Sales of Scorecards Processed Since 2013
150+
Medicaid Rebate Customers
$10B+
Total Payments Processed Through Distribution Contract Management
The Net Revenue Challenge
The average biopharmaceutical company pays more than 40% of gross revenue in rebates, distribution fees, and direct patient support. Government regulations, private payer negotiations, IRA pricing pressures, and evolving distribution models are compressing margins from every direction while compliance obligations grow more complex with every legislative cycle.
Finance and commercial teams must accurately forecast revenues while reconciling data from channel, patient, and operational divisions often without the alignment, infrastructure, or tools to do it reliably. The result is net-price opacity, reserve uncertainty, audit exposure, and millions in preventable revenue leakage.
The ICyte finance and contract operations solutions changes that, connecting regulatory compliance, rebates and discounts, and gross-to-net into a single integrated platform that gives every team the visibility, control, and precision needed to protect and grow net revenue.
Net Revenue Solution Areas
Rebates & Discounts
Full Lifecycle Management Across Every Rebate and Discount Obligation
With billions in annual rebates flowing across thousands of payer contracts, the margin for error is zero. ICyte automates the full lifecycle of government rebates, utilization-based rebates, purchase-based rebates, and chargeback management processing claims with automated validation, dispute management, and payment processing.
Government Rebates Supports Medicaid, TRICARE, Part D (MDP and Inflation), and Part B (Wastage and Inflation) rebate obligations using the lowest level of data received with automated invoice import via RPA, URA preparation, invoice-to-detail reconciliation, variance testing, and payment package assembly and delivery to states.
Utilization-Based Rebates Supports Managed Care contracting and rebate obligations from pharmacy and medical benefit data with contract creation and maintenance, plan-to-payer association management, pharmacy and medical benefit validations, final exclusions, and system-generated reporting packages for paid and excluded claims.
Purchase-Based Rebates Supports chargeback and rebate/fee obligations with contract creation and maintenance, parent-to-child association management, final exclusions, and integrated payment processing workflow with full audit trail.
Chargeback Management Processes EDI 844 and manual debit memos through header and line validations, data resolution workflows, credit memo generation to ERP, and EDI 849 transmission to wholesalers with acknowledgement-triggered reconciliation and full audit trail.
Claims Data Management ICyte solves data retrieval, scrubbing, validation, and reconciliation challenges at scale across pharmacy claims, medical claims, and Claim Level Detail (CLD) from PBMs and commercial health plans.
Regulatory Compliance
Audit-Ready Across Every Government Pricing and Reporting Obligation
Navigating government pricing calculations, state price transparency reporting, and Medicaid rebate obligations requires a system built for that complexity, one that keeps pace with regulatory change without requiring costly manual intervention.
Government Pricing ICyte's highly configurable price type editor supports all CMS, VA, and PHS calculations with full versioning and audit trail. A structured workflow guides data validation through calculation execution and submission with automated reporting, Part B and D inflation monitoring, and built-in drill-down capability at every step.
- Supports AMP, Best Price, ASP, Federal Ceiling Price, FSS, and all required regulatory price types
- Automated data ingestion from ExFactory sales, adjustments, free goods, chargebacks, rebates and fees
- Manager QA/QC, customer review and certification, and pricing delivery to CMS all within a single workflow
- Class of Trade matching and PHS eligibility determination integrated into the calculation process
State Price Transparency Reporting Approximately half of U.S. states have implemented drug price transparency reporting requirements, and no two states have the same rules. ICyte's State Price Transparency solution manages the full compliance lifecycle across your portfolio.
- Legislative repository by state with dates, triggers, and ongoing updates for regulatory changes
- Pricing calculator with auto-generation of reports and what-if modeling
- Due date tracking and grouping by report type
- State registrations, manufacturer portfolio analysis, and report submission managed on your behalf
Gross-to-Net
Accurate Accruals. Reliable Forecasts. Audit-Ready Financial Close.
Gross-to-net (GTN) does not exist in isolation. ICyte connects gross-to-net directly to channel data, patient data, contracts and pricing, and government pricing obligations so that every input is accurate, every accrual is defensible, and every forecast is grounded in real commercial performance data.
GTN Accruals Out-of-the-box accrual methodologies integrated with revenue management systems, URA and Best Price TRICARE calculators, automated data cleansing and adjustments, pre-configured operational reports, full-suite analytics dashboards, and scalability and auditability built in from day one.
GTN Forecasts Out-of-the-box forecasting methodologies, payer mix and returns analog benchmarks, forecasting variance analysis, and GTN what-if analytics scenario modeling including WAC price impacts, contract term changes, IRA implications, and coverage gap and copay patient funnel models.
Why ICyte for Gross-to-Net
Unified Data Foundation
ICyte Data Mart integrating patient, channel, contracts and pricing data into a single GTN foundation
Certified Methodology Library
Methodology library with SOC-certified processes and controls
Real-World Benchmarking
Payer mix and returns analog benchmarks across hundreds of real-world commercialization
Channel Harmonization
Sales, demand, and inventory harmonization across channels
GTN Analytics & Insights
Cross-functional GTN analytics and collaborative industry practices and insights
Expert Advisory Team
CPA and MBA credentialed advisory team with deep pharma finance experience
Fast Facts
Rebate Controls - Up to 10% Savings in Unearned Rebates
ICyte's precision claims management capabilities deliver measurable savings through standard validations (aberrant quantity, invalid provider, invalid plan, date of service, duplicate claims) and advanced validations (formulary non-compliance, coordination of benefits, additional aberrant quantity) with 340B duplicate discount controls leveraging chargeback and 867 data integration.
340B Revenue Leakage Prevention
Integration of 867s and settled chargebacks, filtered covered entity eligibility lists, pharmacy, and product-level exclusions, and third-party 340B-ESP integration with SVT for customers with contract pharmacy policies preventing duplicate discounts across commercial managed care and Medicaid channels.
2,000+ scorecards processed since 2013
Automates distributor scorecard generation, payment processing, and audit trails for DSA fees with a configurable library of industry-standard data quality, inventory, and service level metrics. Supports monthly and quarterly scorecarding, tracks waivers and fee overrides, and integrates price appreciation clawback and government pricing requirements.
Full Transparency with Payment Portal
Eliminates email-based approval workflows replacing them with automated multi-level, serial and parallel payment approvals integrated directly into the invoice workflow, with full transparency throughout the funding and payment process.
Largest Concentration of Net Revenue Expertise
IntegriChain fields the largest concentration of net revenue expertise in the biopharmaceutical industry with over 350 full-time personnel, an average staff tenure of more than 5 years, and 55% of staff with more than 10 years of industry experience. Our GTN advisory team includes CPAs, MBAs, and professionals with deep Big 4 audit backgrounds, biopharma finance experience, and government pricing specialization augmented by an expert advisory practice for advanced analytics, IRA strategy, and commercial contracting guidance.
Impact by the Numbers
350+ Full-Time Net Revenue Personnel
140+ Government Pricing Customers
$230B Net Sales of Scorecards Processed Since 2013
Flexible Operating Models
SaaS
Full access to the ICyte net revenue suite of solutions including government pricing, rebate management, chargeback processing, GTN accruals and forecasting configured to your portfolio and operated by your internal team.
SaaS /Managed Services Hybrid
A combination of platform access and IntegriChain managed services support giving your team strategic control while IntegriChain handles defined operational functions.
Managed Services
IntegriChain's 350+ net revenue personnel act as a seamless extension of your team managing government pricing calculations, Medicaid rebate processing, managed care adjudication, chargeback processing, GTN accruals and forecasting, and state price transparency reporting on your behalf. SOC 1 and SOC 2 compliant, with automated processes, methodology and SOP documentation, integrated reporting and analytics, and a single customer point of contact.